History and Evolution of Dermal Fillers

The list of injection techniques aimed at rehabilitating the volume of facial tissue structures has become popularly known as augmentation. It helps to increase the thickness of the skin and eliminate wrinkles. The alternative names for this procedure are "contour plasty" or " volumetric plasty". The preparations used during the process of its implementation are called dermal fillers or fillers. 

Historical Background

Modern history can be traced back to the 19th century, when scientists first used body fat to eliminate defects in the face area. In 1893, Neuber reported that it was possible to use free body fat to make the face volume more pronounced. As a result, the technique began to develop at a rapid pace and in the 1900s it was used all over the world.

Then Lexer reported the possibility of using fat elements to eliminate cheekbone depression and defects in the chin area. The first institution to use a syringe to inject small amounts of fatty tissue was Bruning. This technique, despite the lack of long-term success, has proven to be a good practice among cosmetologists and patients. 

As a result, specialists from all over the world began to research other techniques of increasing tissue volume. The search for the optimal preparation for soft tissue augmentation began. Despite the achieved results, they are still under way. 

What are the Characteristics of the Ideal Filler of the 21st Century?

First of all, the product should be 100% safe. Particularly, it should have high biocompatibility, do not cause allergic reactions, do not contain poisons and do not provoke pain when used.

Secondly, the effectiveness of the composition plays an important role. It should be easy to use, produce an immediate, lasting and stable effect without the need for further corrections.

In the third place, patient comfort plays an essential role. The product should be ideally suited for outpatient use, be affordable and easy to store and prepare for the procedure. 

The First Filler

By 1970, specialists had tested and presented a number of filler agents. However, none of them succeeded in getting the approval of the Department that controlled  pharmaceutical preparations and similar products. In 1986, as a result of 6.5 years of intensive use of the product, well thought out advanced solutions were developed. And the first products succeeded in obtaining permission to use them to increase the volume of soft tissues. The first developer of such a product was ZYDERM. 

Modern Achievements

Recently, filler production techniques have been developing rapidly. This has led to the creation of products that stimulate the biological response to the medication administered, for example, Saypha (here are other similar products). As a result, the skin gradually thickens and the effect of the treatment lasts for a long time. Modern fillers have become not just fillers, but something more. It is because they stimulate the production of the patient's own collagen. 

Over the last 10 years, there has been a remarkable breakthrough in this area. The list of indications for the use of these preparations has also expanded. Modern standards require that the therapy of the face should be based on the principle "from the inside out", so the cosmetic industry is able to implement all kinds of rejuvenation programs. To date, the search for the ideal agent is going on.